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A food allergy is an abnormal immune reaction to certain proteins in food, with the most common allergens being milk, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat. Normally, food should not trigger an allergic response due to a process called oral tolerance. In this process, proteins in food are broken down into small fragments called oligopeptides by gastric acid and proteases in the stomach and intestines. These oligopeptides reach payer's patches, where M cells are located along the intestinal wall. Learn more by signing up for a free trial on osmosis.org.