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hello and welcome everyone thank you to the panel for such a great presentation they were all so good we appreciate it weamp;#39;ve got a lot of questions so iamp;#39;m going to reintroduce the panel thatamp;#39;s here to answer questions real quick um we have susan buchanan filling in for susan pandia from aggios we have dr lola facili aj from the fda we have dr lipika goyal from boston mass general and we have sofia cornell from citizen yep and i think thatamp;#39;s all and iamp;#39;m melinda bikini with uh the clan your carcinoma foundation and iamp;#39;m american from md anderson wonderful so iamp;#39;m going to get to the first question so this was for dr pandiya thank you for the valuable and challenging work developing inhibitors for idh mutations well we see trials for inacidinib against cca patients with idh2 mutations and sorry this is going to go to susan buchanan no problem thank you melinda and and thank you for the question so um to answer that uh as some people in