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The video discusses the significance of smiling, emphasizing it as a powerful tool for enhancing personal and professional lives. Smiling is linked to increased happiness and health and is a universal expression understood across cultures, transcending the 6,000 languages spoken by the 7.5 billion people in the world. The speaker notes that smiling involves 253 facial muscles, yet many people only smile 5 times a day, falling short of the recommended 20 smiles daily. The research highlights that happy individuals tend to smile more often, suggesting that cultivating this simple habit can lead to greater well-being.