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Brooke Jackson was fired in September 2020 for acting as a whistleblower during Pfizer's phase three trial of their COVID-19 vaccine. Starting on September 8, she observed numerous irregularities, which she reported to her managers, who attributed the issues to being understaffed. Jackson noted significant concerns, including emails from Icon urging Ventavia to investigate severe adverse events and discrepancies in specimen labeling, such as blood samples and nasal swabs being mixed up with other participants' information. On September 16, while staying late at the clinic, she discovered a biohazard bag in the vaccine storage area, adding to her concerns about the trial's integrity.