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Heart failure occurs when the heart is unable to pump enough blood to meet the body's needs. This can be due to weak or damaged ventricular walls, or stiffened and thickened walls that hinder blood flow. Left-sided heart failure leads to fatigue and shortness of breath, as the left ventricle struggles to supply oxygen-rich blood to the body. This can also result in increased blood pressure and fluid buildup in the lungs. Conversely, right-sided heart failure causes blood to accumulate in the veins, leading to edema throughout the body.