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The letter of intent should be specifically tailored and concise, directed to the leader of the program, such as the program director. It is essential for students or IMGs (International Medical Graduates) who have had positive interviews. Rather than sending a generic letter to all programs, the letter should reflect genuine interest and relevance. A free resource on this topic, including a template and examples, is available on the blog at drninalum.com. It is recommended to study this resource while creating your own letter of intent.