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last speaker of today before we have a break on the panel is steve horvath from ucla who i guess will probably talk about epigenetic clocks steve can you hear me yes i can i hope you like my display settings does that look good can you see it looks great yeah okay excellent yeah so i will talk about epigenetic clocks they have been mentioned by others we use methylation to um not only estimate chronologic age but importantly also mortality risk so i want to emphasize that right away um ill start with some studies in mice um i was collected over 2 000 mouse tissue samples they are all being measured on a new array platform called the mammalian methylation array this array is applicable to all mammals and here i just want to show you a completely independent analysis of our mouse clocks so these are strictly test data different brain regions striatum cortex cerebellum um liver also tail interestingly tail samples work beautifully i should mention ear samples work beautifully i dont kno