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hello and welcome to bun medrow we discuss concise medical knowledge that you can fit inside of a bun in this video weamp;#39;re going to be having a look at the various clotting studies that we have available including things like prothrombin time uh aptt and bleeding time and really of understanding what they mean and how we may apply them to various diseases whenever we order a pile of clotting studies though there are three main things that weamp;#39;re interested in and finding out firstly what is the bleeding time secondly whatamp;#39;s the pro thrombin time and lastly what is the aptt or the activated partial thromboplastin time if we have an issue with uh a with our clotting one of these times or multiple of these times is going to be raised because weamp;#39;re taking longer to clot so firstly bleeding time refers to any disease of primary hemostasis and we know that primary hemostasis involves the von willebrand factor and platelets thus if we have a disease of one willow