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oh this was based on a regimen that we designed in the late 1990s which was designed for older patients thereamp;#39;s a typical Milo grade of regiments that we discussed in the one paper only applies to patients less than 60 years of age however most of the myeloid leukemias over my Lourdes plastic anemia as a limb for disease actually in all the patients so patients median age of 65 to 70 thatamp;#39;s where the highest prevalence is and so in order to design a conditioning regimen that could be tolerated we developed a regimen that consists of low dose fluid air beam and a low dose total body irradiation and that regimen has been applied now to more than 2,000 patients and it can be done in the outpatient setting so the patient comes to Seattle and gets analyzed evaluated this donor has been identified and the patient goes through the transplant in the outpatient department if theyamp;#39;re living within a half hour driving radius of the center they can live at home if they are