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In this tutorial from Clinical Physio, Carla discusses essential questions for gathering past medical history, drug history, and social history during a subjective examination. She introduces the acronym "hashtag thread Sox" to remember key medical conditions. Each letter corresponds to specific health issues: Hash (fractures), T (thyroid conditions), H (heart conditions), R (rheumatoid conditions), I (epilepsy), A (asthma and other breathing pathologies), D (diabetes), S (previous use of steroids), O (osteoporosis), C (personal or family history of cancer), and S (history of surgery). The video emphasizes the importance of these inquiries for effective patient assessment.