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right uh thanks for having me can you see my screen no just kidding just kidding weamp;#39;ve done this enough so you should see it um Iamp;#39;m going to talk about a case of driver mutation lung cancer itamp;#39;s nice to meet you all Iamp;#39;m V pad Iamp;#39;m a professor here uh who attends at San Francisco General Hospital and works in epidemiology um all right letamp;#39;s get started um I have a bunch of learning objectives I donamp;#39;t know how many weamp;#39;re going to get through but weamp;#39;ll see what we can do um one question I always have and people talk about is is driver mutation lung cancer better than non-driver mutation lung cancer is single agent pism AB ideal for someone who doesnamp;#39;t have driver mutations but has a pdl1 expression of over 50% letamp;#39;s say 55% why is Disease Control rate and overall survival actually unreliable in single arm studies are waterfall plots visually accurate how much time does surrogate approval save how often