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[Music] hi and welcome back to three size lessons.com UK by the end of this video you should be able to explain the roles of thyroxine and adrenaline in the body you should then be able to explain how thyroxine levels are controlled by negative feedback and all of this is for higher tier students only in a recent video we look to the endocrine system we saw that hormones are chemicals released directly to the bloodstream by glands these hormones then cause an effect in specific target organs now two of the glands are the adrenal glands arent the thyroid gland and were going to be looking at those in this video the adrenal glands are located at the top of the kidneys during times of fear or stress the adrenal glands produce the hormone adrenaline the adrenaline is released into the blood one of the main effects of adrenaline is to increase the heart rate because the heart beating faster more oxygen and glucose are delivered in the blood to the brain and the muscles both oxygen and gl