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menamp;#39;s event was a plenary session talk at ASCO and the reason it was a plenary session talk is that it was both a large clinical trial randomizing patients with newly diagnosed metastatic hormone sensitive disease to adt plus either enzalutamide at a standard dose or a standard anti-androgen the traditional aunt androgens like by khalood amide or flu to mine and in this study there was a docHub survival benefit in favor of the enzalutamide arm by itself that wasnamp;#39;t particularly surprising because we saw a very similar effect in latitude and stampede with abiraterone which is a drug thatamp;#39;s not dissimilar to a parabola and ends luta minor not dissimilar from each other so one of the reasons it was a plenary session talk was because about 45% of the patients in Enza men were allowed to get chemotherapy this was the physician and the patientamp;#39;s choice in other words it wasnamp;#39;t a pre-specified randomization but one of the biggest questions