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so ask us is one of the most common findings on a pap smear so letamp;#39;s talk about it I am Dr Toya board certified OB GYN and we are going to talk about what causes ask us so first of all what is ask us it means atypical squamous cells have unknown significance so when we collect some cells from your cervix during the pap smear or your cervical cancer screening the computer analyzes the cells and they can tell that the cells are abnormal but theyamp;#39;re really not sure how abnormal so itamp;#39;s of unknown significance it doesnamp;#39;t necessarily mean that something is wrong these cells just look abnormal and itamp;#39;s one of those results that can be caused by a ton of different things so ask us can be caused by information recent sex hormone changes menopause infection and of course if you have abnormal cells in these cervix caused by HPV virus so itamp;#39;s rare that if you have this result youamp;#39;re going to have pre-cancel cancer changes on the cervix but i