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In this tutorial, Cathy from Level Up RN discusses best practices for IV route medication administration. She highlights the appropriate catheter sizes for different types of patients: a 16-gauge catheter for trauma patients, an 18-gauge for surgical cases, and a 20-, 22-, or 24-gauge for medical patients. For effective IV insertion, she advises placing the patient's arm in a dependent position to enhance blood flow and using a tourniquet 5 to 6 inches above the insertion site. Additionally, for older patients, a blood pressure cuff is recommended instead of a tourniquet. The video concludes with a quiz to test the viewer's knowledge of the covered concepts.