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thank you very much for the introduction and also for the invitation to present our work on RNA modification detection we have very large overview this year shows our genome and the genes are transcribed to generate the RNA and weamp;#39;re working on computational methods to analyze transcriptomics sta the set of all of these rnas in our cell the reason why weamp;#39;re interested in it is because thereamp;#39;s such a complexity because of alternative sing start and Ides so that each gene can actually generate a lot of different versions of those rnas and so thereamp;#39;s also poster if you want to see that from my team poster number one talking a bit more about those aspects but today I want to talk about one additional thing that is even if the RNA sequence is the same it can still be functionally different and thatamp;#39;s because of RNA modifications these RNA modifications they are chemical alterations of these nucleotides and they are written by um writer enzymes and the