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The text discusses how autoimmune reactions can cause significant joint damage, often due to the release of damaged particles from the joint into surrounding tissues. The body mistakenly identifies these particles as foreign and produces antibodies against them, leading to autoimmune reactivity where the body attacks its own joint tissues. Additionally, food allergies contribute to this issue by forming immune complexes that can infiltrate small blood vessels in the joints, resulting in ischemia. This combination of factors is particularly relevant in conditions like osteoarthritis.