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scientists say theyve slowed and even reversed some of the devastating effects of motor neuron disease the treatment works in only two percent of patients but the team at the University of Sheffield has described it as truly remarkable and a moment of Hope for the whole disease the mnd association said there was a mounting confidence in the therapy well the research was carried out in part by the Neuroscience Institute at Sheffield university in England its director is Professor Dame Pamela Shaw thank you very much for coming on the program my pleasure so a a rare Glimpse here of good news could you just talk us through exactly how this works in in the simplest possible terms so um as as you mentioned two percent of patients with m d have a a slight fault in this sod1 sod1 Gene and what um the tougheston therapy does it has to be injected via a lumbar puncture into the cerebrospinal fluid and it lowers the level of the sod1 protein and the toxic effects to multi-neurons that arise fr
