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In considering how to structure a start-up, it's essential to focus on the business model, which outlines how a company creates value while delivering products or services to customers. Historically, companies organized themselves around functional departments, leading to traditional org charts. However, a modern approach emphasizes a different diagram that illustrates the various components of a business. This involves a framework of nine boxes to describe any company, from large corporations to small teams, highlighting the interconnected elements that drive the business's structure and function.