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so again my name is nil chenrack i am the medical director of the kidney pancreas transplant program at a brigham and womens hospital but im also a transplant immunologist with a long-standing interest in regulatory t cells and today im going to talk to you a little bit about a novel anti-specific t-reg type of therapy that were hoping will replace conventional immunosuppression in our transplanted patients so whats the problem well you know by any measure kidney transplantation is a success you have 95 of patients who receive a kidney transplant having functional survival at one year however this comes at great cost because you have to put the patients on toxic lifelong non-specific immunosuppression and as we all know immunosuppression has a number of side effects specifically it can cause infection and the rates of uh malignancy skyrocket you can see it 10 years its like 400 percent compared to a normal population what is less known about immunosuppression is that in our pati
