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hello everyone welcome back to another video on the genomics boot camp back again with another video on linkage disequilibrium this is the first part of the finishing two when we are actually computing the linkage disequilibrium this time by hand i believe this is an interesting piece of knowledge so it's worthwhile to look at so what we know so far so ld characterizes the degree of relationship between two loci as always and r square is the commonly used measure of the ld computed with the equation below and here we are at the first of the two examples i will show you today the first one is the very basic one and actually you might recall this two by two table from the previous videos when we look at the r square equation it is clear what we need to compute and that is the proportion of a proportion of b and the proportion of the joint occurrence of a and b therefore we are interested what is in this segment or cell in in this other one for the b and the joint occurrence of a and b t...