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letamp;#39;s look into more factors that affect how quickly the liver can clear drug from the body using the well stirred model this time weamp;#39;re going to explore hepatic blood flow in the equation itamp;#39;s represented by Q subh normally about 1,500 mL of blood flows through the liver every minute unfortunately there really isnamp;#39;t an easy way to directly measure hepatic blood flow there are techniques involving Tracer substances injected into the blood or ultrasound scans but they used more for research than for day-to-day practice so the pharmacist is usually left trying to anticipate possible problems based on the patientamp;#39;s condition there are various disease states that can reduce blood flow we have to consider them when deciding on doses for our patients in what situations would hepatic blood flow decrease incase one common situation is congestive heart failure in heart failure the heart is not pumping as efficiently less blood is being pushed out of the l
