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okay so welcome back everybody this is the second webinar of today so to this webinar is going to be about some of the product development pathways and strategies that some 80 MPs have taken for commercialization so this should be complementary to some of the other webinars that we will be doing so its not going to be an overview of 80 MPs at all its going to go straight into some of the products and what they are so that aim then of this is just to really summarize using two models some of the regulatory and scientific pathways and decisions that were made to to get on to the market in the EU so were not going to revise in any detail any of the regulatory procedures how they work what they are assume some knowledge of that and I think Joelle is going to talk about that in a couple of weeks time so if youre not so familiar we can look out for his webinar when it comes up soon so the focus will also be on the European approval path were not so much FDA just for times sake so Im go