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the simplified molecular input line entry system is a specification in form of a line notation for describing the structure of chemical species using short ASCII strings smiles strings can be imported by most molecule editors for conversion back into two-dimensional drawings or 3-dimensional models of their molecules the original smiles specification was initiated by David whining or at the US EPA midcontinent ecology division laboratory in Duluth in the 1980s acknowledged for their parts in the early development were Gillman veeth and Rose Rousseau and Albert Leo and Corwin Hans for supporting the work and Arthur whining or and Jeremy Scofield for assistance in programming the system the Environmental Protection Agency funded the initial project to develop smiles it has since been modified and extended by others most notably by daylight chemical information systems in 2007 an open standard called open smiles was developed by the Blue obelisk open source chemistry community other line