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so when using your small clear 10 millimeter steri fit use the cotton filter whenever possible to avoid clogging prepare the cotton filter after cooking or dissolving drop the cotton from the package without touching it with your fingers into the cooker apply a couple drops of sterile water to moisten the cotton when opening the cooker keep the cotton filter inside the sterile packaging while you prepare your drugs this will help decrease contact with bacteria or viruses attach the steri-fill to the syringe filter comes in a blister pack opening by pulling on the tab and leaving it halfway attached when the filter still covered by the package press your thumb into the divot until the filter hub lifts if you use a syringe with a needle in a straight line connect your syringe and filter hub gently but firmly push then twist until tight to make the syringe have an airtight seal if you use a needless syringe the filter goes where the needle would be with the cotton positioned uprig