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use your big green 15 millimeter steri-filter if you use a syringe with a needle in a straight line connect the syringe in the filter hub gently but firmly push then twist until it goes on tight to the syringe to make an airtight seal if you use a needleless syringe the filter goes where the needle would go filtering drugs can take anywhere between 20 to 60 seconds place the steri-fit filter pull on the syringe plunger slowly to prevent air bubbles allow for the delay of drugs entering the syringe without holding the plunger remove the air by tapping the area below the bubbles and push the plunger to remove recap the needle and prepare your injection site please remember after youamp;#39;ve finished injecting that you put your syringe in a sharps container you