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so alpha-fetoprotein has been a biomarker and liver cancer for some time its exact role has been somewhat difficult to define its not a very good screening test in and of itself because only about 2/3 of liver cancer make AFP so if youre using it as a screening test youll miss 1/3 of patients so thats why screening should be imaging based like an ultrasound and then if you want to add AFP to that thats acceptable we know that patients with a high AFP have a worse prognosis than those who dont have a high AFP and in the context of making treatment decisions we now have data that suggests that patient with a high AFP benefit from Remy serum AB in the second line setting and this study comes from the this data comes from the docHub to study this was a follow-up study from the first day of Rey Mysterio map which took all patients and you remember Raimi Sierra maam is a monoclonal antibody to the bed chef receptor and in the first docHub study for patients who progressed on to RAF ni
