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platelet-rich plasma or PRP injections can offer robust long-term pain and symptom relief for people suffering from thumb joint arthritis but not all PRP is the same and overpaying for inferior quality PRP will result in poor outcomes in this video I will go over what platelet-rich plasma is discuss how it works and review data from a randomized control trial comparing PRP injections to cortisone injections Iamp;#39;ll also review what you need to look out for so you donamp;#39;t pay for inferior quality PRP hey everyone Dr Jeff Peng here thumb osteoarthritis specifically at the carpo metalcarpal joint also known as the trapezium metacarpal joint is a common cause of Pain and Disability despite it being a very small joint symptoms can be debilitating it can restrict thumb movement cause weakness and instability of the thumb and reduce pinch and grip strength all of this will make day-to-day activities rather painful and while traditional treatment options for some some osteoarthritis