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hi Iamp;#39;m Andrew Jourdan one of the rheumatologist at BJamp;#39;s eHealth we use a range of medications to treat our inflammatory conditions including biologic medications some of these injections and one of the common problems we get asked about his injection site reactions by that I mean redness irritation or swelling at the site of the injection there are range of things we can do to help minimize this firstly I suggest you take the medicine out of the fridge for about thirty minutes prior to the injection this will also reduce the pain of the injection secondly is ice the area before and after for about ten minutes if they continues to be ongoing injection site problems taking paracetamol or any histamine prior to the injection can also reduce the problems if there are ongoing problems which are docHub I would usually switch to a different medication which can even be within the same class or a different family and this will usually fix the problem so in summary these ar