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this is going to be a presentation about characterizing and correcting rare mutations in CFTR if youamp;#39;re looking for another session I think transplant is next door and then clinical trials and access are both upstairs on the fourth floor thinking the San Antonio rooms so nobodyamp;#39;s leaving so apparently everybodyamp;#39;s in the right room thatamp;#39;s great so weamp;#39;re going to have presentations first from Katherine Tuggle who is our director of research and then John or Jed Mahoney is going to follow and Jed is a scientist at the CE FFT lab up in Lexington Massachusetts again weamp;#39;ll be capturing questions submitted at C F F dot C F dot IO so any questions that you have based upon the presentation or perhaps you came with questions that are may not be addressed during the presentations feel free to enter the end of them in and Iamp;#39;ll moderate a QA at the end of Jedamp;#39;s presentation so without any further ado Iamp;#39;m going to go ahead and t