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we wanted to investigate whether cooling is an adjunct to primary PCI would further reduce the infarct size so this was a pilot planning 50 patients anterior steamy within six hours of symptom onset randomized to standard of care which is primary PCI plus experimental group which was primary PCI plus in the rescuer cooling associated with one up to one litre of hotel line before primary PCI so we cool down the patient before we push the wire to open the coronary and this was a pilot study so we there are many many exploratory endpoints we wanted to learn whether this is feasible and safe was that you know we could with this new system we could go down to thirty three point three degrees at the time of the perfusion by primary PCI and this is more than one point one degree lower than in previous endovascular cooling status so we learn that you know we can do it and we learn that at least based on this sample we can do it safely and I think itamp;#39;s a good background
