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[Music] hello so this video will briefly discuss log T log T is an important parameter in predicting lipophilic City now liquid Felicity determines whether or not the drug will be able to cross the lipid membranes so aka absorption log P octenol over water equals the log concentration of drug and octenol and the concentration of drug in water to visualize this we can take a flask for a halfway with water and halfway with optional which is an oily substance add the drug to it give it a shake and here is what well see so in this example there are lets say five drug molecules in water and one drug molecule in the oil meaning that in this case the drug is more hydrophilic than lipophilic affecting membrane absorption all right so the log partition has whats known as a log scale and this log scale ranges from negative 5 to 5 the negative numbers being for the hydrophobicity hydrophilicity and the positive numbers being for them the pop Felicity and as you can see to determine the result