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In screening tests for conditions like ovarian cancer or non-invasive prenatal tests for Down syndrome, it's crucial to understand the positive predictive value (PPV) from your doctor. For instance, the PPV for the non-invasive test for Down syndrome is typically around 80%, meaning that out of ten positive results, eight are correct and two are incorrect. If the test is conducted in a low-risk pregnancy, the doctor may not specify whether one or nine of the ten results are accurate, but the screening indicates a possibility that follow-up testing is necessary. This awareness helps to clarify the uncertain nature of the results and the need for further testing to confirm the findings.