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In America, the blood industry is a multibillion-dollar market, valued at $3.3 billion in 2021, with blood making up over 2% of U.S. exports. There is a constant demand for human blood, with current supplies at a critical one-day level, leading to potential life-or-death shortages. The FDA's blood donation policies, particularly the ban on gay men donating, are being questioned in light of new scientific studies. Major companies in blood collection, like Grifols, CSL Plasma, Takeda's BioLife, and Octapharma, are involved in plasma collection, where donors are compensated. This plasma is vital for therapies developed by pharmaceutical companies, highlighting the complexities surrounding blood as a public health resource.