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great well uh its a pleasure to be here and talk to you today about hemato oncology applications of immune repertoire sequencing and before i get into the content of my talk uh id like to mention that immune repertoire sequencing data is is a tremendously versatile data type and it can be applied to immuno-oncology research immunology and infectious disease research and as i will describe today hematology research where it can be used to detect and track b-cell and t-cell clones of interest so for a bit more granularity on it on the presentation im going to start with a background on immune repertoire sequencing before proceeding to describe some of the reasons why the field has migrated towards immune repertoire sequencing as a tool for hematology research and then after that ill discuss spectra typing analysis as a tool to interpret repertoire data before finally finishing the presentation with a discussion of somatic hypermutation and its impact on clonality and clone tracking