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The video tutorial discusses the applications of immune repertoire sequencing in hemato oncology research. The speaker highlights the versatility of immune repertoire sequencing data in immuno-oncology, immunology, infectious disease, and hematology research. The presentation covers the background of immune repertoire sequencing, reasons for its use in hematology research, spectratyping analysis for data interpretation, and the impact of somatic hypermutation on clonality and clone tracking.