Fix style in the mnda in a few clicks

Aug 6th, 2022
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How to fix style in the mnda

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what is MND MN d stands for motor neurone disease about 5000 people in the UK have MND at any one time motor neurons are nerves in your brain and spinal cord that carry messages to your muscles telling them what to do the term MND covers a group of similar conditions that affect these nerve cells which can lead to loss of movement weakness and wasting early signs of the disease might include mild weakness clumsiness tripping over or slurred speech but each individual experiences the disease in a different way this means MND is difficult to diagnose and there are no definitive tests it is usually identified by ruling out other conditions seeing how symptoms progress also helps but it can take time before a diagnosis is confirmed there is currently no cure and MND is life-shortening however specialist support to manage symptoms and an assessment of social care needs can help people find services and support and prolong independence this can help to achieve the best possible quality of li

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Increasing evidence shows that disease spreading in amyotrophic lateral sclerosis (ALS) follows a preferential pattern with more frequent involvement of contiguous regions from the site of symptom onset.
In LMN lesions, weakness often fits a pattern of muscles supplied by the same nerve root (myotomal pattern) or same peripheral nerve. Another common LMN pattern is the length dependent pattern (i.e., the longest nerves are affected the most).
Weakness usually has a particular pattern in time, anatomy, or both. Difficulty working overhead, combing or brushing hair, ascending stairs, or getting off a toilet seat all imply proximal muscle weakness.
Around 2 per cent of all MND patients have inherited a SOD1 gene mutation, which causes the body to create a toxic form of the SOD1 protein, which leads to nerve cell death. Tofersen, the new medication from Biogen, is designed to reduce the toxic SOD1 protein in the body.
With ALS, you may first have weakness in a limb that develops over a matter of days or, more commonly, a few weeks. Then, several weeks to months later, weakness develops in another limb. Sometimes the initial problem can be one of slurred speech or trouble swallowing.
Patterns of weakness include symmetric or asymmetric weakness without sensory loss or focal midline proximal symmetric. The classification of MNDs is broadly divided into heritable or sporadic and by the de- gree of upper or lower motor neuron involvement.
ALS often begins with muscle twitching and weakness in an arm or leg, trouble swallowing or slurred speech. Eventually ALS affects control of the muscles needed to move, speak, eat and breathe. There is no cure for this fatal disease.
The different types of MND cause similar symptoms and have three stages: early, middle, and advanced. The diseases progress at different speeds and vary in severity.

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