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Patients with heart failure and secondary mitral regurgitation have a poor prognosis. Surgical treatment has not shown to reduce hospitalizations or death, but transcatheter mitral valve repair may improve outcomes. In a trial with 614 patients, those who received transcatheter repair had fewer heart failure hospitalizations. The primary endpoints were hospitalizations for heart failure within 24 months and device-related complications at 12 months, with lower rates in the device group.