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- PMDD versus PMS, whats the difference between the two, and how do we treat it? Thats what this video is about. Im Dr. Tracey Marks, a psychiatrist and I do videos on mental health education and self improvement. This video is based on a viewer question from Mel. Can you please do a vid on PMDD? Im having trouble knowing if its that or bipolar II. Thank you Mel. PMDD stands for premenstrual dysphoric disorder, and this is not to be confused with premenstrual syndrome, or PMS. PMS is changes in mood during certain parts of your menstrual cycle and it affects about 80% of women. The mood changes can be mild to moderate. In fact, some women will just see it as feeling a little moody the week before their menstrual cycle. PMDD is a severe form of PMS. Its almost like turning into a werewolf when the full moon rises. (woman screaming) (monstrous sound) - [Girl] Mommy? - And for some people, its just that drastic. It affects three to 8% of women, so its not as common as PMS. PMD