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welcome to this video on registration my name is mike jenkinson and im going to be talking to you about epi distortion correction and how that interacts with registration epi if you remember is the pulse sequence that we use in order to acquire functional and diffusion images so this is equally relevant for functional and diffusion imaging though most of the examples that ill be giving will be related to functional imaging when weve got a functional image or as i say a diffusion where weve got an epi image and we want to register that to our structural image and then ultimately to our standard space weve got a few more problems than we would have if we just had a structural to standard registration or a structural structural registration problem and thats because the epis have distortions and they have loss of signal which we need to be able to correct for and thats what the epi distortion correction is all about so registration of epi is more tricky than other things because th