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[Music] hello and welcome im dr raj sharina budrypod im board certified in internal medicine and todays video is all about hashimotos thyroid disease hashimotos thyroiditis is autoimmune thyroid disease it sounds like a rare and exotic disorder but its actually one of the most common autoimmune conditions and the number one cause of hypothyroidism worldwide the thyroid gland is one of the most important endocrine glands in your body and its actually located in your neck and its shaped like a butterfly how do we diagnose hashimotos thyroid disease so hashimotos is diagnosed by the presence of the thyroid peroxidase antibody or the tpo antibody on your blood work the tpo antibody causes an autoimmune attack on the thyroid gland what does this mean on a microscopic level so this is what a normal thyroid looks like under the microscope we have follicular cells that are lining a pink vicious fluid made out of proteins called colloid in hashimotos thyroid disease the tpo antibody