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hi Terry Shane fl4 UAB School of Medicine when studies are combined in a meta-analysis theyre generally done using one of two statistical techniques a fixed effect or Rand effects model in this video Im going to give a very broad overview at 30,000 foot view of what these two models are and when theyre used so meta-analysis is a two-stage process in the first step we calculate a summary statistic for each of the individual studies included in the analysis that could be we calculate a relative risk and odds ratio hazard ratio risk difference etc then in step 2 were going to calculate an overall treatment effect of all these summary statistics and usually what it is is a weighted average of the summary statistics and the weight tends to be an inverse of the variance so well talk about this more toward the end of this video now these statistical techniques that we use to calculate this overall treatment fact fall into usually one of two broad groups of fixed effects model or a rando
