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hey welcome back to the channel my name is Sim London and today we are going to talk about a new paper written by David Sinclair and his team that they have been working for many years about the information Theory of Aging doing so the study itself is called loss of epigenetic information as a cause of mammalian aging and yeah published January 12. here are some of the highlights of the study cellular responses to double standard DNA breaks I wrote the epigenetic landscape so thats kind of you know the scratches on the CD or vinyl that over time accumulates that causes you know aging and the Damage this loss of epigenetic information accelerates the Hallmarks of Aging so there are up to like 10 Hallmarks of Aging like loss of proteases telomer shortening DNA damage and those kind of things epigenetic miscommunication these changes are reversible by epigenetic reprogramming and by this they refer to like activating different like genes and Pathways in the body like sirtuins and using