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Health Technology Assessments (HTAs) are systematic evaluations of the clinical, economic, and social implications of healthcare technologies, including drugs, medical devices, and diagnostic tests. They aim to inform decision-making regarding the adoption and use of these technologies. HTAs typically involve reviewing evidence on safety, efficacy, and cost-effectiveness, while also considering factors such as patient outcomes, ethical issues, social implications, and feasibility of implementation in healthcare settings. Various stakeholders, including policymakers, healthcare providers, and patients, utilize HTAs to guide decisions about healthcare technologies. This tutorial is sponsored by Nested Knowledge, a platform supporting systematic literature reviews and meta-analyses.