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we continue our work on identifying biochemical abnormalities within immune cells in patients with lupus and weve been doing that for a number of years at least 20 years and weve been successful and identified molecules that are normally expressed in which can serve as targets for treatment and indeed some of them have been picked up by industry and theyre put you in clinical trials several of them also in doing so will try to identify molecules that can serve as biomarkers molecules that I can help us diagnose the disease a libertarian hopefully follow disease activity down on more recently we have established the t-cell generic expression array which we can use to evaluate the expression of a number of genes simultaneously and through some mathematical manipulations to generate what we call a tease of score and use that for today to do to help us make diagnosis every make a differential diagnosis much easier and we believe it can help us follow disease activity and make treatment