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a blow fill seal manufacturing line is a compact filling Suite that takes bulk drug product he septic fills it in newly formed BFS resin containers ensures the filled units meet quality standards and preps the containers for secondary and tertiary Packaging in the following video chapters we will divide up the BFS line into a series of subjective areas to outline the steps a BFS container should go through from filling to initial secondary packaging for this example we will use a bottle pack 460 rotary BFS machine from ralog on a 0.5 ml filled product at 25 units per cycle as a result some of the details will vary by BFS machine but the overall proc process is relatively consistent across all BFS filling Suites