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Professor Tim Spector, a leading expert in gut health and nutrition, argues that exercise alone is not effective for weight loss. He criticizes calorie counting and the focus on calorie, fat, and sugar content promoted by the food industry, stating that it distracts from the quality of food. Spector emphasizes the need for a paradigm shift in how we perceive food and points out the lack of long-term evidence supporting calorie counting for sustained weight loss. He also highlights the relationship between gut microbiota quality and mental health issues like depression and anxiety, advocating for personalized nutrition as a more effective approach.