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Did your doctor order a test called ANA ? Did the test come back positive? A positive ANA test is one of the most common referral reasons in my rheumatology office. Join me in this lecture where I will discuss about: What is the ANA test and why was it ordered? Is the ANA titer important? Is the ANA pattern suggestive of a specific disease? And What are the most frequent causes for a positive ANA? The first questions that I would like to address is What is the ANA test and why was it ordered? ANA stands for antinuclear antibodies. As their name suggests they are antibodies. Antibodies are proteins produced by our immune system in response to a trigger, most of the time an infection. They are part of our body defense mechanism against foreign invaders. Antinuclear antibodies are a specific type of antibody directed against the nucleus of a cell. They can appear in your bloodstream when your immune system is fired-up to fight something foreign like viruses, bacteria or a medicatio
