Transform your daily workflows and Extract Data Clinical Trial Agreement

Aug 6th, 2022
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How to Extract Data Clinical Trial Agreement

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um Im excited today to kick off the fall clinical trials toolkit series um our first one is the office of sponsored programs clinical trial agreement review and negotiation um today we have Rachel humberson she is the interim assistant director um from research office and office of sponsored programs and we also have um Julie even though I practiced it Julie Im going to mess it up Anna okay is that right yeah okay she is a negotiator with research with the research office and office of sponsored programs um before I read their um their bios and a fun fact about them again we are offering continuing education to WVU employees so if um you would like CES please indicate that and please put your name um an email address in the chat so for attendance purposes um Im trying to think if theres anything else oh if you have a question during this um feel free to put it in the chat well be watching it and um I will stop Rachel and Julie and let them know what your question is and then also

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Data in a clinical trial are generated and collected by: The investigator. Study staff.Paper Case Report Forms (CRFs) Site staff can carry the CRF to wherever they need it. Site staff dont need to worry about access to computers and passwords. Relatively easy to amend if changes are required during the study.
Source data are contained in source documents (original records or certified copies). Source Documents are those documents where data regarding study subjects are first recorded and serve as the basis for the information submitted to the Sponsor on the case report forms.
A Data Transfer Agreement (DTA) is a legal contract governing the transfer of non-human subject data or completely de-identified human subject data. It sets out the related protections, rights, and obligations of both parties and delineates the specific purpose(s) for which the data may be used.
Source data includes all information in original records and certified copies of original records of clinical findings, observations, or other activities in a clinical investigation used for reconstructing and evaluating the investigation.
Source Data Verification (SDV) is a method that clinical research organizations (CROs) can use to ensure the data theyre collecting is accurate. It involves comparing a studys source data against its final report, allowing for the identification of any errors before they become problematic or get published.
Source data is the first place the information is documented. Often a site will complete a source data agreement form to identify the source. The auditor verifies the following when conducting SDV or SDR during the audit: Informed consent form (ICF) is signed prior to any study procedures being conducted.
A clinical trials agreement should describe and acknowledge responsibilities, terms of collaboration, requirements for payment and reimbursement, publication and intellectual property terms, indemnification and or insurance, subject injury coverage, guidelines for dispute resolution, grounds for termination of contract
While source document verification (SDV) aims to compare recorded data against the source documents to ensure a match, the purpose of source document review (SDR) is to ensure the quality of the source documentation itself.

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