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in medicine we overwhelmingly use treatments which are safe and effective but there are still often uncertainties we often dont know which is the best of the currently available treatments so to give a concrete example of this statins are probably the most commonly prescribed treatment in the whole of the developed world tens of millions of patients take these treatments every day but we still dont know which is the best of the many different statin treatment regimes we need to do a randomized control trial we need to take a large group of people who are being offered a new treatment and give half of them one treatment half of them the other treatment and then follow them up to see how theyre doing now at the moment because doctors dont have good quality evidence to guide them they will arbitrarily choose to give their patient one treatment or another and effectively this is what happens every day in medicine but if a doctor participates in a trial to formally compare one statin tr