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[Music] hi there im carol and welcome to our gcp mindset channel our topic today is on the trial master file audits and inspection readiness well look up preparation strategies you and your team will need to ensure audit or inspection readiness lets begin [Music] the trial master file holds the entire story or audit trail of the clinical trial investigation and is therefore succumb to good clinical practice audits and inspections to evaluate compliance with the protocol the trial safe conducts and the quality of the data obtained and that all the activities of a clinical trial can be reconstructed from start to finish if youre conducting a clinical study whether youre still using paper tmf or already switched to electronic tmf its important to be prepared to host the audit or inspection anytime before we go right into some tips lets be clear about these two terms gcp audits are planned to comply with the sponsors quality assurance program audits could be performed at any stage